Gain a Pound, Gain a Pimple

We make a liver protein called Sex Hormone Binding Globulin (SHBG), and it carries around our hormones making sure they don’t over act. Too much and we don’t have enough free hormone too little and we have too much. I think of it as a scrotal hormone, odd, I know, but there you have it, the same stuff , or darn near the same stuff, in guys, is made in the scrotum. Yuk right, but you won’t forget the thing will you! Here’s a new fact: Weight gain will decrease SHBG. This is mediated by both direct liver effects, and the amount of cholesterol and hormone production, as well as the amount of insulin in the circulation which is increased by being over weight or obese. In fact insulin is so tied in with SHBG you can use blood testing of it as a predictor of who is going to become diabetic.